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  • 產(chǎn)品名稱： Furimazine
  • 產(chǎn)品貨號： CS15359
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 2400
  • 數(shù)量：
    庫存： 5
  • 規(guī)格： 1mg
  • 產(chǎn)品信息
  • 如何訂購
    貨號（Catalog No.）
    CS15359 
    別名
    PBI 3939
    純度(Purity）
    97.57%
    產(chǎn)品描述(Description)
    Furimazine is an imidazopyrazinone substrate. NanoLuc (Nluc) paired with Furimazine produced 2.5 million-fold brighter luminescence in mammalian cells relative to Oluc-19 with Coelenterazine.
    體外活性
    Furimazine is a Coelenterazine analogue. Measurement of luminescence intensity from cells expressing Nluc reveals that maximal signal is attained at about 10-20 μM Furimazine[1]. The apparent Km for purified NanoLuc (Nluc) using either Furimazine or Coelenterazine is ~10 μM, while the maximum luminescence (i.e., apparent Vmax) is ~30-fold higher for Furimazine than for native Coelenterazine.
    分子式
    C24H19N3O2
    分子量
    381.435
    參考文獻(xiàn)
    [1]Hall MP, et al. Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol. 2012 Nov 16;7(11):1848-57.
    儲存和溶解度
    DMSO:100 mg/mL (262.17 mM)
    Powder: -20°C for 3 years
    In solvent: -80°C for 2 years