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  • 產(chǎn)品名稱： Research Grade Sotigalimab
  • 產(chǎn)品貨號： CSD68911
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 2480
  • 數(shù)量：
    庫存： 5
  • 規(guī)格： 100μg
  • 產(chǎn)品信息
  • 如何訂購
    Description
    The FDA has granted an orphan drug designation to sotigalimab (APX005M) as a potential therapeutic option for patients with soft tissue sarcoma, according to announcement from Apexigen Inc., the drug developer. A novel, humanized monoclonal antibody, sotigalimab was designed stimulate antitumor immune response and to target CD40, which is a key co-stimulatory receptor that serves to activate innate and adaptive immune systems. When sotigalimab binds to CD40 on antigen-presenting cells, it induces a multifaceted immune response that brings several components of the immune system together to attack the cancer.icon
    Catalog No.
    CSD68911
    Host species
    Humanized
    Species reactivity
    Human
    Form
    Liquid
    Storage buffer
    0.01M PBS, pH 7.4.
    Concentration
    2.54 mg/ml
    Purity
    >95% 
    Clonality
    Monoclonal
    Isotype
    IgG1-Kappa
    Applications
    Research Grade Sotigalimab Biosimilar
    Target
    Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,Bp50,CD40L receptor,TNFRSF5,CDw40,CD40
    Purification
    Protein A or G purified from cell culture supernatant.
    Endotoxin level
    Please contact with the lab for this information.
    Expression system
    Mammalian cells
    Accession
    P25942
    Stability and Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
    Alternative Names
    APX005M, APX-005, APX-005-M, APX-005M, CAS: 2305607-45-6
    Note
    For research use only .Not suitable for clinical or therapeutic use.