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  • 產(chǎn)品名稱: H3B-8800
  • 產(chǎn)品貨號(hào): CS110572
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購: 1200
  • 數(shù)量:
    庫存: 100
  • 規(guī)格: 1mg
  • 產(chǎn)品信息
  • 如何訂購
    生物活性
    H3B-8800 is a potent and orally active SF3B splicing modulator. H3B-8800 direct interaction with the SF3b complex and shows anti-cancer activity. H3B-8800 has the potential for the research of acute myeloid leukemia (AML) with SF3B1 mutant[1].
    Cas 號(hào)
    1825302-42-8
    分子量
    555.71
    Formula
    C31H45N3O6
    純度
    98%
    性狀
    固體
    顏色
    Yellow to orange
    運(yùn)輸條件
    Room temperature in continental US; may vary elsewhere.
    儲(chǔ)存條件
    store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 6 months ,-20°C for 1 month
    參考文獻(xiàn)
    [1]. Seiler M, et al. H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers. Nat Med. 2018 May;24(4):497-504.
    Note
    For research use only.