瀏覽量: 463
- 產(chǎn)品名稱: Research Grade Denosumab ( 地舒單抗 )
- 產(chǎn)品貨號: CSD00157
- 貨期: 現(xiàn)貨
- 價格與訂購: 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(Catalog No.)
CSD00157
通用名INN
Denosumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Denosumab is a novel, fully human IgG2 monoclonal antibody specific to receptor activator of nuclear factor kappa-B ligand (RANKL), suppresses bone resorption markers in patients with a variety of metastatic tumors and is being investigated in multiple clinical trials for the prevention and treatment of bone metastases. Chemically, it consists of 2 heavy and 2 light chains. Each light chain consists of 215 amino acids. Each heavy chain consists of 448 amino acids with 4 intramolecular disulfides. FDA approved on June 1, 2010.
別名(Alternative names)
AMG162
靶點;物種(Specificity target name;species)
TNFSF11/CD254[Homo sapiens]
種類(Species)
Homo sapiens
受體鑒定(Receptor identification)
IgG2-kappa
分子量(MV)
144700.00 Da
CAS
615258-40-7
存儲條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .