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  • 產(chǎn)品名稱： Research Grade Raxibacumab ( 雷昔庫(kù)單抗 )
  • 產(chǎn)品貨號(hào)： CSD00167
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 2480
  • 數(shù)量：
    庫(kù)存： 100
  • 規(guī)格： 100μg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    貨號(hào)（Catalog No.）
    CSD00167
    通用名INN
    Raxibacumab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    產(chǎn)品描述(Description)
    Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
    別名(Alternative names)
    IDEC-C2B8
    靶點(diǎn);物種(Specificity target name;species)
    Anthrax protective antigen [Bacillus anthracis]
    活性研究（體外/體內(nèi)研究）(Activity in vitro)
    In vitro, PA-824 exhibits the high activity against multidrug-resistant clinical isolates from Asia (India and South Korea) and from throughout the United States (MIC <1 μg/ml) and is equally active against the drug-sensitive and multidrug-resistant isolates of M. tuberculosis (MICs range, 0.039 to 0.531 μg/ml). A recent study shows that single-nucleotide polymorphisms of PA-824 resistance genes (fgd1 [Rv0407] and ddn [Rv3547]) don't significantly affect the PA-824 MICs (≤ 0.25 μg/ml).
    種類(Species)
    Homo sapiens
    受體鑒定(Receptor identification)
    IgG1-lambda
    分子量(MV)
    142844.53 Da
    CAS
    565451-13-0
    存儲(chǔ)條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .