瀏覽量: 99
- 產(chǎn)品名稱: Research Grade Aselizumab ( 阿塞珠單抗 )
- 產(chǎn)品貨號(hào): CSD00177
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購: 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(hào)(Catalog No.)
CSD00177
通用名INN
Aselizumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
別名(Alternative names)
HuDreg-55
靶點(diǎn);物種(Specificity target name;species)
SELL/CD62L [Homo sapiens]
活性研究(體外/體內(nèi)研究)(Activity in vitro)
Dexamethasone (Hexadecadrol) regulates several transcription factors, including activator protein-1, nuclear factor-AT, and nuclear factor-kB, leading to the activation and repression of key genes involved in the inflammatory response.
Dexamethasone potently inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) release from A549 cells with EC50 of 2.2 nM. Dexamethasone (EC50=36 nM) induces transcription of the β2-receptor is found to correlate with glucocorticoid receptor (GR) DNA binding and occurred at 10-100 fold higher concentrations than the inhibition of GM-CSF release. Dexamethasone (IC50=0.5 nM) inhibits a 3×κB (NF-κB, IκBα, and I-κBβ), which is associated with inhibition of GM-CSF release.
種類(Species)
Humanized
受體鑒定(Receptor identification)
IgG4-nd
CAS
395639-53-9
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .