瀏覽量: 112
- 產(chǎn)品名稱: Research Grade Erlizumab ( 厄利珠單抗 )
- 產(chǎn)品貨號(hào): CSD00182
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購(gòu): 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購(gòu)
貨號(hào)(Catalog No.)
CSD00182
通用名INN
Erlizumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
別名(Alternative names)
rhuMAb
靶點(diǎn);物種(Specificity target name;species)
ITGB2/CD18 [Homo sapiens]
活性研究(體外/體內(nèi)研究)(Activity in vitro)
Leukadherin-1 pretreatment reduces secretion of interferon (IFN)-γ, tumour necrosis factor (TNF) and macrophage inflammatory protein (MIP)-1β by monokine-stimulated NK cells. It also reduces secretion of IL-1β, IL-6 and TNF by Toll-like receptor (TLR)-2 and TLR-7/8-stimulated monocytes. Leukadherin-1 modulates NK cell cytokine secretion and does not modulate Syk activation in NK cells. LA1 increases CD11b/CD18-dependent cell adhesion to fibrinogen with 50% effective concentration (EC50, the effective concentration for a 50% increase in adhesion) values of 4 μM.
種類(Species)
Humanized
受體鑒定(Receptor identification)
IgG1-nd
分子量(MV)
148000.00 Da
CAS
211323-03-4
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .