瀏覽量: 78
- 產(chǎn)品名稱: Research Grade Alirocumab ( 阿利蘇單抗 )
- 產(chǎn)品貨號: CSD00281
- 貨期: 現(xiàn)貨
- 價格與訂購: 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(Catalog No.)
CSD00281
通用名INN
Alirocumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which are a novel class of anticholesterol therapeutics. From this family, it was the first agent to receive FDA approval. The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety. PCSK9 inhibition facilitates more LDL-C clearance from the blood.
別名(Alternative names)
REGN727,SAR-236553
靶點;物種(Specificity target name;species)
PCSK9[Homo sapiens]
種類(Species)
Homo sapiens
受體鑒定(Receptor identification)
IgG1-kappa
分子量(MV)
146000.0 Da
CAS
1245916-14-6
存儲條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .