瀏覽量: 86
- 產(chǎn)品名稱: Research Grade Fasinumab ( 法司努單抗 )
- 產(chǎn)品貨號: CSD00286
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購: 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(Catalog No.)
CSD00286
通用名INN
Fasinumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Fasinumab has been used in trials studying the basic science and treatment of Sciatica, Back Pain, Low Back Pain, Osteoarthritis, Hip, and Abdominal Pain Upper, among others.
別名(Alternative names)
REGN475,SAR164877
靶點(diǎn);物種(Specificity target name;species)
NGF/NGFB [Homo sapiens]
活性研究(體外/體內(nèi)研究)(Activity in vitro)
Ro 08-2750 binds to the NGF dimer thereby probably inducing a change in its conformation such that NGF cannot bind to p75NTR anymore.
Ro 08-2750 (10 nM) completely rescues cells from undergoing NGF-induced SK-N-MC 10^3 cells death.Ro 08-2750 (5-10 μM; 8?hours) increases differentiation and apoptosis in myeloid leukemia cells.Ro 08-2750 inhibits survival of human AML lines and patient cells.Ro 08-2750 inhibits MSI2 RNA-binding and alters MSI2 gene signature.
種類(Species)
Homo sapiens
受體鑒定(Receptor identification)
IgG4-kappa
CAS
1190239-42-9
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .