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- 產品名稱： Recombinant Human ALOX15B protein
- 產品貨號： CSP00782
- 貨期： 現貨
- 價格與訂購： 1800
- 數量：
庫存： 100
- 規(guī)格： 50μg 100μg 1mg
- 產品信息
- 如何訂購
概述（Summary）
英文全稱
Recombinant Human ALOX15B protein
純度（Purity）
>90% as determined by SDS-PAGE
內毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白構建（Construction）
A DNA sequence encoding the human ALOX15B (Arg253-Glu490) was fused with His tag
Accession #
O15296
表達宿主（Host）
E.coli
種屬（Species）
Homo sapiens (Human)
預測分子量（Predicted Molecular Mass）
27.14 kDa
制劑（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運輸方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩(wěn)定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介紹
Isoform A:
Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids (PUFAs) generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE (Probable). Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE (Probable. Oxygenates arachidonyl derivatives such as 2-arachidonoylglycerol (2-AG) leading to the production and extracellular release of 15-hydroxyeicosatetraenoic acid glyceryl ester (15-HETE-G) that acts as a peroxisome proliferator-activated receptor alpha agonist . Has the ability to efficiently class-switch ALOX5 pro-inflammatory mediators into anti-inflammatory intermediates . In addition to metabolize free PUFAs hydrolyzed from phospholipids, directly oxidizes PUFAs esterified to membrane-bound phospholipids . Has no detectable 8S-lipoxygenase activity on arachidonate but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE (Probable). May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells .
Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids (PUFAs) generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE (Probable). Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE (Probable. Oxygenates arachidonyl derivatives such as 2-arachidonoylglycerol (2-AG) leading to the production and extracellular release of 15-hydroxyeicosatetraenoic acid glyceryl ester (15-HETE-G) that acts as a peroxisome proliferator-activated receptor alpha agonist . Has the ability to efficiently class-switch ALOX5 pro-inflammatory mediators into anti-inflammatory intermediates . In addition to metabolize free PUFAs hydrolyzed from phospholipids, directly oxidizes PUFAs esterified to membrane-bound phospholipids . Has no detectable 8S-lipoxygenase activity on arachidonate but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE (Probable). May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells .
分子別名（Alternative Names）
Polyunsaturated fatty acid lipoxygenase ALOX15B,15-lipoxygenase 2,15-LOX-2,Arachidonate 15-lipoxygenase B,15-LOX-B,Arachidonate 15-lipoxygenase type II,Linoleate 13-lipoxygenase 15-LOb .
Note
For research use only .
地 址：
產品銷售：
E - mail ：
郵 編：
Amily
