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  • 產品名稱: Recombinant Human DNASE1 protein
  • 產品貨號: CSP00843
  • 貨期: 現(xiàn)貨
  • 價格與訂購: 1800
  • 數(shù)量:
    庫存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產品信息
  • 如何訂購
    概述(Summary)
    英文全稱
    Recombinant Human DNASE1 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構建(Construction)
    A DNA sequence encoding the human DNASE1 (Gly19-Ala259) was fused with His tag
    Accession #
    P24855
    表達宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預測分子量(Predicted Molecular Mass)
    27.9 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs . Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA . Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization . Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) . NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation . Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation.
    分子別名(Alternative Names)
    Deoxyribonuclease-1,Deoxyribonuclease I,DNase I,Dornase alfa.
    Note
    For research use only .