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  • 產(chǎn)品名稱： Recombinant Human SERPINA5 protein
  • 產(chǎn)品貨號(hào)： CSP01408
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 1800
  • 數(shù)量：
    庫(kù)存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    英文全稱
    Recombinant Human SERPINA5 protein
    純度（Purity）
    >90% as determined by SDS-PAGE
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    內(nèi)毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構(gòu)建（Construction）
    A DNA sequence encoding the human SERPINA5 (Ser43-Pro406) was fused with His tag
    Accession #
    P05154
    表達(dá)宿主（Host）
    E.coli
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    種屬（Species）
    Homo sapiens (Human)
    預(yù)測(cè)分子量（Predicted Molecular Mass）
    41.31 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
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    穩(wěn)定性&儲(chǔ)存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
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    電泳圖（SDS-PAGE image）
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    背景（Background）
    Serpin A5, also well known as protein C inhibitor (PCI), is a member of the human serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, serpinA5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin, and plays a role in the processes of blood coagulation and fertilization. Serpin A5 also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion, and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore, recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator), suggesting a novel function in the regulation of tissue repair and regeneration. Similar to serpins C1 and D1, the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
    分子別名（Alternative Names）
    PCI, PLANH3, PROCI,Serpin A5,Protein C inhibitor,PAI3,PAI-3
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    Note
    For research use only. Not suitable for clinical or therapeutic use.