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  • 產(chǎn)品名稱： Recombinant Human CCN1 protein
  • 產(chǎn)品貨號(hào)： CSP01413
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 1800
  • 數(shù)量：
    庫(kù)存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    概述（Summary）
    英文全稱
    Recombinant Human CCN1 protein
    純度（Purity）
    >90% as determined by SDS-PAGE
    內(nèi)毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構(gòu)建（Construction）
    A DNA sequence encoding the human CCN1 (Leu178-Asp381) was fused with His tag
    Accession #
    O00622
    表達(dá)宿主（Host）
    E.coli
    種屬（Species）
    Homo sapiens (Human)
    預(yù)測(cè)分子量（Predicted Molecular Mass）
    24.47 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景（Background）
    背景介紹
    Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
    分子別名（Alternative Names）
    Cellular communication network factor
    Cysteine-rich angiogenic inducer 61
    Insulin-like growth factor-binding protein 10
    Short name:
    IBP-10
    Short name:
    IGF-binding protein 10
    Short name:
    IGFBP-10
    Protein CYR61
    Protein GIG1
    Note
    For research use only .