瀏覽量: 48
- 產(chǎn)品名稱: Recombinant Human C5 protein
- 產(chǎn)品貨號: CSP01851
- 貨期: 現(xiàn)貨
- 價格與訂購: 1800
- 數(shù)量:
- 規(guī)格: 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述(Summary)
英文全稱
Recombinant Human C5 protein
純度(Purity)
>90% as determined by SDS-PAGE
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白構(gòu)建(Construction)
A DNA sequence encoding the human C5 (Thr678-Arg751) was fused with GST tag
Accession #
P01031
表達宿主(Host)
E.coli
種屬(Species)
Homo sapiens (Human)
預(yù)測分子量(Predicted Molecular Mass)
33.62 kDa
制劑(Formulation)
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運輸方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩(wěn)定性&儲存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復(fù)溶(Reconstitution)
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景(Background)
背景介紹
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes . C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes . C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
分子別名(Alternative Names)
Complement C5,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4,
Note
For research use only .