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  • 產(chǎn)品名稱: Recombinant Human GRK2 protein
  • 產(chǎn)品貨號(hào): CSP01938
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購(gòu): 1800
  • 數(shù)量:
    庫(kù)存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    概述(Summary)
    英文全稱
    Recombinant Human GRK2 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構(gòu)建(Construction)
    A DNA sequence encoding the human GRK2 (Asp398-Leu640) was fused with GST tag
    Accession #
    P25098
    表達(dá)宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預(yù)測(cè)分子量(Predicted Molecular Mass)
    52.85 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them . Key regulator of LPAR1 signaling . Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor . Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner . Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity . Inhibits relaxation of airway smooth muscle in response to blue light .
    分子別名(Alternative Names)
    Beta-adrenergic receptor kinase 1,Beta-ARK-1,G-protein coupled receptor kinase .
    Note
    For research use only .