瀏覽量: 67
- 產(chǎn)品名稱: Recombinant human Amyloid beta(aa1-42) protein
- 產(chǎn)品貨號: CSP11005
- 貨期: 現(xiàn)貨
- 價格與訂購: 1800
- 數(shù)量:
- 規(guī)格: 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述(Summary)
英文全稱
Recombinant human Amyloid beta(aa1-42) protein
純度(Purity)
>95%
Accession #
P05067
表達宿主(Host)
E.coli
種屬(Species)
Homo sapiens (Human)
背景(Background)
背景介紹
Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimer's disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimer's disease patients to create the senile plaques characteristic of the disease.
分子別名(Alternative Names)
Abeta; Amyloid beta; beta-Amyloid Peptide