瀏覽量: 83
- 產(chǎn)品名稱: Recombinant Human Thioredoxin/TXN protein,N-His Tag
- 產(chǎn)品貨號: CSP11007
- 貨期: 現(xiàn)貨
- 價格與訂購: 1800
- 數(shù)量:
- 規(guī)格: 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述(Summary)
英文全稱
Recombinant Human Thioredoxin/TXN protein,N-His Tag
純度(Purity)
>90% as determined by SDS-PAGE
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
蛋白構(gòu)建(Construction)
A DNA sequence encoding the Human TXN (Val2-Val105) was fused with the N-His Tag
Accession #
P10599
表達宿主(Host)
E.coli
種屬(Species)
Homo sapiens (Human)
預(yù)測分子量(Predicted Molecular Mass)
13.91kDa
制劑(Formulation)
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.6 .
運輸方式(Shipping)
In general, proteins are provided as lyophilized powder. They are shipped out with blue ice unless customers require otherwise.
穩(wěn)定性&儲存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復(fù)溶(Reconstitution)
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
電泳圖(SDS-PAGE image)
背景(Background)
背景介紹
Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin / TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Thioredoxin / TXN nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Thioredoxin / TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
分子別名(Alternative Names)
Thioredoxin,Trx,ATL-derived factor,ADF,Surface-associated sulphydryl protein,SASP,Allergen: Hom s Trx,TRDX, TRX, TRX1
Note
For research use only .