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  • 產(chǎn)品名稱： Anti STK11 Mouse Monoclonal Antibody
  • 產(chǎn)品貨號： CS26158
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 2800
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 100μl 200μl
  • 產(chǎn)品信息
  • 如何訂購
    Catalog Number
    CS26158   
    Gene Symbol
    STK11, LKB1, PJS, hLKB1 
    Description
    Anti STK11 Mouse Monoclonal Antibody 
    Background
    Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response, and functions as a tumour suppressor. Recent studies have uncovered a large number of somatic mutations of the STK11 gene that are present in lung, cervical, breast, intestinal, testicular, pancreatic and skin cancer. 
    Immunogen
    A synthetic peptide from the internal region of STKwhich includes the mutation of P281L, human origin. 
    Applications
    ELISA, WB, IHC 
    Recommended Dilutions
    ELISA: 1:1000-1:5000 
    WB: 1:100-1:1000 
    IHC: 1:50-1:200 
    Concentration
    0.5mg/ml 
    Host
    mouse
    Format
    Liquid 
    Clonality
    Monoclonal 
    Purity
    Purified from ascites 
    Preservative
      no

    Constituents
      PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol 
    Species Reactivity
      Recognizes P281L mutated, but not wild-type STK11 of vertebrates. 
    Storage Conditions
      Store at -20°C. Avoid freeze / thaw cycles 
    Immunofluorescence:
    Immunofluorescence of cells expressing STK11 proteins with Anti STK11 (P281L) antibody. HEK293T cells were transfected with pCDNA3-GFP STK11 (WT) plasmid (left column) or pCDNA3-GFP STK11 (P281L) plasmid (right column), then fixed and stained with Anti STK11 (P281L) monoclonal antibody (Cat. #CS26158). 
    Note
    For research use only .