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  • 產(chǎn)品名稱： Anti IDH1 Mouse Monoclonal Antibody
  • 產(chǎn)品貨號(hào)： CS26136
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購： 2800
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 100μl 200μl
  • 產(chǎn)品信息
  • 如何訂購
    Catalog Number
    CS26136 
    Gene Symbol
    IDH1 
    Description
    Anti IDH1 Mouse Monoclonal Antibody 
    Background
    Isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Mutations of Arg-132 in IDH to Cys, His, Leu or Ser abolish magnesium binding and the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R-2-hydroxyglutarate. Elevated levels of R-2-hydroxyglutarate are correlated with an elevated risk of malignant brain tumors. 
    Immunogen
    Recombinant proteins of human IDH1 (amino acids 1-240). 
    Applications
     ELISA, WB, IHC, IP 
    Recommended Dilutions
    ELISA: 1:1000-1:5000 
    WB: 1:100-1:1000 
    IHC: 1:50-1:100 
    Concentration
    1 mg/ml 
    Host
    mouse 
    Format
     Liquid 
    Clonality
    Monoclonal 
    Isotype
    IgG 
    Purity
    Purified from ascites 
    Preservative
    no
    Constituents
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol 
    Species Reactivity
    Anti IDH1 antibody recognizes IDH1 of vertebrates. 
    Storage Conditions
    Store at -20°C. Avoid freeze / thaw cycles 
    Western blot

    Western blot analysis of recombinant IDH1 protein. Purified His-tagged IDH1 protein (amino acids 1-240) (Cat.#10198) was blotted with anti IDH1 mouse antibody (Cat.# CS26136). 

    Note
    For research use only .