瀏覽量: 179
- 產(chǎn)品名稱(chēng): Research Grade Siltuximab ( 塞妥昔單抗 )
- 產(chǎn)品貨號(hào): CSD00196
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購(gòu): 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購(gòu)
貨號(hào)(Catalog No.)
CSD00196
通用名INN
Siltuximab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment of adult patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. MCD is a rare blood disorder caused by dysregulated IL-6 production, proliferation of lymphocytes, and subsequent enlargement of the lymph nodes. It is administered as a 1 hour intravenous infusion every 3 weeks.
別名(Alternative names)
CLLB8,CNTO 328
靶點(diǎn);物種(Specificity target name;species)
IL6[Homo sapiens]
種類(lèi)(Species)
Chimeric
受體鑒定(Receptor identification)
IgG1-kappa
分子量(MV)
145000.00 Da
CAS
541502-14-1
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .