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  • 產(chǎn)品名稱： Research Grade Bevacizumab ( 貝伐珠單抗 )
  • 產(chǎn)品貨號(hào)： CSD00004
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 2480
  • 數(shù)量：
    庫(kù)存： 100
  • 規(guī)格： 100μg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    貨號(hào)（Catalog No.）
    CSD00004
    通用名INN
    Bevacizumab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    產(chǎn)品描述(Description)
    Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.Bevacizumab, a humanized monoclonal antibody,specifically binds to all VEGF-A isoforms with high affinity.
    別名(Alternative names)
    12-IgG1,F(ab)-12 IgG1,Fab-12 IgG1,rhuMAb-VEGF
    靶點(diǎn);物種(Specificity target name;species)
    VEGFA[Homo sapiens]
    活性研究（體外/體內(nèi)研究）(Activity in vitro)
    Bevacizumab, a humanized monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity, and inhibits its interaction with VEGFR-1 and VEGFR-2. Experimental analysis shows that the EC50 of Bevacizumab to bind VEGF analyzed by ELISA is 0.18 μg/mL. Binding kinetics assays show similar results that Bevacizumab inhibits the VEGF-induced proliferation of HUVEC with an IC50 value of 0.047±0.0081 μg/mL.
    受體鑒定(Receptor identification)
    IgG1-kappa
    分子量(MV)
    149000.00 Da 
    CAS
    216974-75-3
    存儲(chǔ)條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .