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  • 產品名稱: Recombinant Human EP300 protein
  • 產品貨號: CSP01592
  • 貨期: 現(xiàn)貨
  • 價格與訂購: 1800
  • 數量:
    庫存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產品信息
  • 如何訂購
    概述(Summary)
    英文全稱
    Recombinant Human EP300 protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    Accession #
    Q09472
    表達宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability. Mediates acetylation of histone H3 at 'Lys-27' (H3K27ac). Also functions as acetyltransferase for non-histone targets, such as ALX1, HDAC1, PRMT1 or SIRT2. Acetylates 'Lys-131' of ALX1 and acts as its coactivator.
    分子別名(Alternative Names)
    Histone acetyltransferase p300,Short name:
    p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein propionyltransferase p300
    Note
    For research use only .