瀏覽量: 47
- 產(chǎn)品名稱: Recombinant Human FGF21 protein
- 產(chǎn)品貨號: CSP01583
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購: 1800
- 數(shù)量:
- 規(guī)格: 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述(Summary)
英文全稱
Recombinant Human FGF21 protein
純度(Purity)
>90% as determined by SDS-PAGE
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
Accession #
Q9NSA1
表達(dá)宿主(Host)
E.coli
種屬(Species)
Homo sapiens (Human)
制劑(Formulation)
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運(yùn)輸方式(Shipping)
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩(wěn)定性&儲存(Stability &Storage)
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復(fù)溶(Reconstitution)
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景(Background)
背景介紹
Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat/low-carbohydrate diet.Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.
分子別名(Alternative Names)
Fibroblast growth factor 21,Short name:FGF-21
Note
For research use only .